Neck Pain, Rheumatoid Arthritis and Oral Contraceptives

oral contraceptives neck pain rheumatoid arthritisA study published this summer in the journal Arthritis and Rheumatism looking at the use of oral contraceptives and improvements in Rheumatoid Arthritis symptoms adds to the evidence suggesting a connection between female hormones and this possible cause of neck pain. Around two-thirds of RA patients suffer from problems in the cervical spine, with the thoracic and lumbar spine usually less affected. Researchers at the University of Manchester in England used data from women with recent onset of inflammatory polyarthritis and assessed the number who had and had not used oral contraceptives since the diagnosis. The data appears to show a connection between better functional outcome in (female) RA patients using oral contraceptives prior to and at the time of diagnosis compared to women who had never used oral contraceptives. The study authors noted however that the significance of the association only stands in those patients with moderate or severe disability at onset, rather than low level functional disability.

What is Rheumatoid Arthritis?

Rheumatoid Arthritis is an inflammatory disorder that produces symptoms of joint pain, fatigue, fever, and even mood disturbances in sufferers. It is associated with an autoimmune dysfunction and is more prevalent in women than in men, with that trend becoming more pronounced in recent years, an effect blamed on an increased proportion of women smoking (despite less people smoking overall), lower vitamin D levels in many women, and the lower doses of oestrogen used in contraceptives. A study published last year found that the disease occurs in around 1.5million Americans and affects their professional and personal lives, as well as being associated with a shorter lifespan; around 70% of those diagnosed with Rheumatoid Arthritis are women. Up to half of all RA patients are prevented from working by their illness withing 10-20 years after initial diagnosis and the condition costs more than $9billion in healthcare costs, and possibly more than $39billion estimated in indirect costs.


Patients with Rheumatoid Arthritis frequently have neck pain, and the condition, along with ankylosing spondylitis and other inflammatory arthropathies is a common cause of cervical spinal dysfunction. Rheumatoid Arthritis has the potential to lead to very serious complications from subluxations at C1-C2 where the spinal cord itself can become compressed and paralysis or permanent nerve and spinal cord damage may occur. Patients with RA and signs of inflammation, joint degeneration, and symptoms at this level may be able to manage the condition with conservative therapy including physical manipulation and non-surgical traction. Neck surgery may be appropriate in some cases to stabilize the cervical spine through spinal fusion.

How Do Oral Contraceptives Affect RA?

The follow-up period for those included in this data-set averaged almost five years and measurements of functional ability were taken during this time. Patients who had used oral contraceptives prior to their diagnosis of RA had better functional outcomes on follow-up than those who had not used OCs prior to diagnosis. The data also showed an association between OC use at the time of diagnosis and improved functional outcome in comparison to no use of OCs at this time. Of course, association does not imply causality and it may be that some other factor, closely aligned with the use of oral contraceptives is in fact responsible for the purported benefit.

neck pain rheumatoid arthritisThe women whose data was used in the study included 663 women who had not used OCs after diagnosis and 265 who had. The researchers also observed better functional outcomes in women who were taking OCs at the start of the study compared to women who had previously taken OCs but were not currently taking them. All of the women in the group who had taken OCs were under fifty years old and had not had a hysterectomy or gone through menopause during the follow-up period.

What Conclusions Can We Draw from the Study?

The overriding message from the study appears to be that young women have little reason to worry about using oral contraceptives as regards the potential ramifications for Rheumatoid Arthritis and may even have improved functional outcomes as a result of the drugs. Clearly there are other concerns for women using oral contraceptives but the effects on RA do not appear to be one of them. The lead researchers, Dr. Symmons noted that the possible biological mechanisms behind the association are intriguing to consider, especially given that the earlier use of OCs appears to have benefits several years afterwards. Certainly the research does not suggest that women are better off using oral contraceptives in comparison to regular medication for Rheumatoid Arthritis, such as methotrexate, however, women who are reticent about taking oral contraceptives for fear of worsening their neck pain from Rheumatoid Arthritis may feel reassured by this study.

References

Camacho, E. M., Lunt, M., Farragher, T. M., Verstappen, S. M. M., Bunn, D. K. and Symmons, D. P. M. (2011), The relationship between oral contraceptive use and functional outcome in women with recent-onset inflammatory polyarthritis: Results from the Norfolk Arthritis Register. Arthritis & Rheumatism, 63: 2183–2191.

Elena Myasoedova, Cynthia S. Crowson, Hilal Maradit Kremers, Terry M. Therneau, Sherine E. Gabriel. Is the incidence of rheumatoid arthritis rising? Results from olmsted county, minnesota, 1955-2007. Arthritis & Rheumatism, 2010.

Helmick, C.G., Felson, D.T., et al, Estimates of the Prevalence of Arthritis and Other Rheumatic Conditions in the United States, Part I. Arthritis and Rheumatism, Vol. 58, No. 1, January 2008, pp 15–25.

641 replies
  1. http://tinyurl.com/22q6nzro
    http://tinyurl.com/22q6nzro says:

    Thanks for the marvelous posting! I genuinely enjoyed reading it,
    you could be a great author. I will remember to bookmark
    your blog and will often come back down the road. I want to encourage that you continue
    your great writing, have a nice day!

    Reply
  2. http://tinyurl.com
    http://tinyurl.com says:

    Hey! This is kind of off topic but I need some guidance
    from an established blog. Is it very difficult to set
    up your own blog? I’m not very techincal but I can figure things out pretty quick.

    I’m thinking about setting up my own but I’m not sure
    where to start. Do you have any points or suggestions?
    Thank you

    Reply
  3. http://tinyurl.com/28a3b8rr
    http://tinyurl.com/28a3b8rr says:

    Write more, thats all I have to say. Literally, it seems as though you relied on the
    video to make your point. You definitely know what youre talking about, why
    waste your intelligence on just posting videos to your blog when you could be giving us something informative to read?

    Reply
  4. tinyurl.com
    tinyurl.com says:

    I am now not certain the place you are getting your info, however good topic.

    I must spend some time studying more or figuring out
    more. Thank you for excellent info I was on the lookout for
    this info for my mission.

    Reply
  5. tinyurl.com
    tinyurl.com says:

    Hi there! I could have sworn I’ve visited your blog before but after browsing through many of the articles I realized it’s new to me.
    Nonetheless, I’m certainly pleased I discovered it and I’ll be bookmarking it and checking back regularly!

    Reply
  6. tinyurl.com
    tinyurl.com says:

    Do you have a spam issue on this site; I also am a blogger, and I was wanting to know your situation; many of us have created some nice practices and we are looking to swap methods with
    other folks, why not shoot me an e-mail if interested.

    Reply
  7. coupon
    coupon says:

    Very great post. I simply stumbled upon your blog and wanted to say that I’ve truly enjoyed
    browsing your weblog posts. In any case I’ll be subscribing in your rss feed and
    I hope you write once more very soon!

    Have a look at my homepage :: coupon

    Reply
  8. http://tinyurl.com/
    http://tinyurl.com/ says:

    Hi, I do think this is an excellent web site. I stumbledupon it 😉 I may
    return once again since i have book marked it.

    Money and freedom is the best way to change, may you be rich and continue to guide other people.

    Reply
  9. http://tinyurl.com
    http://tinyurl.com says:

    Unquestionably believe that which you stated. Your favorite reason seemed to be on the internet the easiest thing to be aware of.

    I say to you, I definitely get irked while people consider worries that
    they just do not know about. You managed to hit the nail upon the top and defined out the whole thing without having side-effects , people can take a signal.
    Will probably be back to get more. Thanks

    Reply
  10. tinyurl.com
    tinyurl.com says:

    Good post. I learn something new and challenging on blogs
    I stumbleupon every day. It will always be useful to read through articles from other authors and use something from
    their sites.

    Reply
  11. tinyurl.com
    tinyurl.com says:

    Hi fantastic website! Does running a blog like this take a lot
    of work? I have absolutely no understanding of programming however I had been hoping to start my own blog soon. Anyway, if you have
    any ideas or techniques for new blog owners please share.
    I understand this is off topic but I simply wanted to ask. Cheers!

    Reply
  12. http://tinyurl.com/
    http://tinyurl.com/ says:

    I blog often and I really appreciate your information. This
    article has truly peaked my interest. I am going to bookmark your site and keep checking for new details about
    once a week. I subscribed to your Feed as well.

    Reply
  13. tinyurl.com
    tinyurl.com says:

    Just want to say your article is as astonishing.
    The clarity for your post is just cool and that i could assume you are a professional on this
    subject. Well along with your permission allow me to seize your feed to stay
    up to date with drawing close post. Thanks one million and please continue the gratifying work.

    Reply
  14. http://tinyurl.com
    http://tinyurl.com says:

    I do not know whether it’s just me or if everybody else encountering problems
    with your blog. It seems like some of the written text on your content are running off the screen. Can somebody else please comment and let me know
    if this is happening to them as well? This could be a problem
    with my web browser because I’ve had this happen previously.
    Kudos

    Reply
  15. WayneSef
    WayneSef says:

    Когда вы боретесь с расстройством, связанным с употреблением алкоголя, вам может казаться, что конца не видно, но вы не должны страдать в одиночестве. Сегодня существует множество вариантов лечения, которые помогут вам излечиться от алкоголизма и вернуться к здоровой и полноценной жизни.
    Различные факторы, такие как история болезни, система поддержки и личная мотивация, могут сыграть свою роль в успехе вашего выздоровления. Лечение должно проходить под наблюдением группы медицинских специалистов в реабилитационном центре. По всей стране в центрах лечения алкоголизма работают профессионалы, которые проведут вас через все этапы процесса выздоровления – от детоксикации до жизни после реабилитации. Считайте их своей круглосуточной системой поддержки, которая будет радоваться вашим успехам и вместе с вами преодолевать любые трудности.
    Помните, что преодоление алкоголизма – это процесс. Менее половины людей рецидивируют после достижения одного года трезвости. Это число уменьшается до менее 15% после пяти лет трезвости. Чтобы получить наибольшие шансы на долгосрочную трезвость после завершения стационарной или амбулаторной программы, вам следует участвовать в местных группах поддержки и продолжать консультации. Лечение алкоголизма – это инвестиция в ваше будущее. Оно изменит к лучшему не только вашу жизнь, но и жизнь окружающих вас людей, таких как члены семьи и друзья.

    http://www.furniterra.ru/news/portal/a3324/

    Reply
  16. HaroldRab
    HaroldRab says:

    Что такое гибкие кабели?
    Самый простой кабель – это одножильный провод с пластиковой оболочкой.
    Он может гнуться и сохраняет этот изгиб – если вы не делаете это слишком часто, потому что иначе провод ломается.
    Такие простые кабели используются в домашних установках.
    После установки кабель остается нетронутым в течение десятилетий.
    Такие твердые провода не подходят для многих других применений, где кабели должны быть гибкими и эластичными.
    Здесь проводники в жилах состоят из нитей – пучков тонких проволок, которые можно сгибать миллионы раз, в зависимости от конструкции, не ломая и не теряя свойств тока или передачи данных.
    Одно из самых неприятных мест для кабеля – тяговая цепь. Здесь кабели питания, сервопривода и передачи данных расположены близко друг к другу и перемещаются вперед-назад по мере работы машины.
    Иногда со скоростью более пяти метров в секунду с ускорением, превышающим ускорение силы тяжести более чем в пять раз.
    Кабели проложены в тяговой цепи таким образом, что они изгибаются только в одном направлении.
    КГ 3х70+1х50-0,38

    Reply
  17. DavidSLULK
    DavidSLULK says:

    Slot Lucky jet money game has gained popularity in the field of online casino. The main reason is the simplicity of betting game strategy. Beginners have access to a demo lucky jet, in which they can use luckyjet winning trick. Also, any user has the opportunity apk download for free. The promo code for mobile version gives an additional bonus during the game

    Reply
  18. Jeremymef
    Jeremymef says:

    The best lucky jet casino will allow you to earn money quickly and efficiently. You can choose any language and a different method of depositing and withdrawing funds. To do this, you need to register lucky jet 1 wine. The registration method is very simple, you need to enter personal information, the region and the casino will be available to any beginner virtual game

    Reply
  19. Jeremymef
    Jeremymef says:

    how does the lucky jet works
    Tell me where you can play the game lucky jet 1 win in India. Signals in the telegram channel using the prediction hacking bot. Strategies and tricks earn money best 2022. Tips how to play lucky jet 1 win. Official website with reviews of the game. Sign up at the casino with a bonus and a promo code for free spin. Download the APK app for free

    Reply
  20. RichardTraib
    RichardTraib says:

    A dinheiro em uma casa de apostas. Estratégias populares, truques e táticas do jogo para ganhar dinheiro. Baixe o aplicativo para o telefone gratuitamente. Bônus de inscrição para cada jogador

    Reply
  21. Davidnug
    Davidnug says:

    в букмекерской конторе 1 win. Азартная краш игра в казино 1вин. Стратегия заработка денег. Как вывести средства с баланса. Бонус промокод при регистрации на официальном сайте. Скачать APK на телефон.

    Reply
  22. Robertothex
    Robertothex says:

    https://na-telefon.biz
    заказать поздравление по телефону с днем рождения
    поздравления с Днем Рождения по телефону заказать по именам
    заказать поздравление с Днем Рождения по мобильному телефону
    заказать поздравление с днем рождения по именам
    заказать поздравление с днем рождения на телефон

    Reply
  23. Jeremymef
    Jeremymef says:

    Jogo A dinheiro multiplayer que permite ganhar dinheiro apostando em um grafico. Altos indices e pagamentos. Bonus do codigo promocional 2022.

    jogar no Casino 1 win Yu

    Reply
  24. Davidnug
    Davidnug says:

    lucky jet игра
    в букмекерской конторе 1 win. Азартная краш игра в казино 1вин. Стратегия заработка денег. Как вывести средства с баланса. Бонус промокод при регистрации на официальном сайте. Скачать APK на телефон.

    Reply
  25. Davidronge
    Davidronge says:

    Comentarios bater jogo na casa de apostas 1 win. Como jogar e ganhar dinheiro em.

    Estrategia e truques para ganhar no 1 win Casino. Analogo do jogo aviator por Dinheiro. Jogo Predictor hack

    Reply
  26. DavidSLULK
    DavidSLULK says:

    Многопользовательская игра на деньги, которая позволяет зарабатывать деньги делая ставки на график. Высокие коэффициенты и выплаты. Бонус по промокоду 2022.

    играть в казино 1 win

    Reply
  27. local news
    local news says:

    Its like you learn my thoughts! You appear to understand so much about this, like you wrote the guide in it or something. I think that you simply could do with a few percent to drive the message home a little bit, but other than that, this is great blog. A great read. I’ll definitely be back.

    Reply
  28. joker123
    joker123 says:

    Definitely believe that which you said. Your favorite justification appeared to be at
    the net the simplest thing to keep in mind of.
    I say to you, I certainly get annoyed whilst other people think about concerns
    that they plainly do not realize about. You managed to
    hit the nail upon the top and defined out the whole thing without having side-effects ,
    other people could take a signal. Will probably be
    back to get more. Thanks

    Reply
  29. coupon
    coupon says:

    I like what you guys are usually up too. This sort of clever work and coverage!

    Keep up the superb works guys I’ve incorporated you
    guys to my personal blogroll.

    Here is my web page … coupon

    Reply
  30. vanauken.net
    vanauken.net says:

    Our team provide only the hottest Big Black Dick gilf adult vidz in a number of categories.Sit back and jerk on these
    milfs whores tube collection. Here are some largest massive dark
    dick adult vidz on the net. It’s hard to find a exciting website like this, so don’t miss out.

    Explore more on gangbang black blonde (vanauken.net)

    Reply
  31. Dewa Poker
    Dewa Poker says:

    You could certainly see your enthusiasm in the article you write.
    The sector hopes for more passionate writers such as you who
    aren’t afraid to mention how they believe.
    At all times go after your heart.

    My web page – Dewa Poker

    Reply
  32. Tim
    Tim says:

    Piick out which year of outcomes you would like to see, dating
    alll the way back to 1992, byy deciding on the relevant year beneath.

    Here iss my blog – Homme page (Tim)

    Reply
  33. slot gacor
    slot gacor says:

    Its such as you learn my mind! You appear to know a lot about this,
    such as you wrote the book in it or something. I feel that you just can do with a few p.c.
    to force the message home a bit, however instead of that, this is great blog.
    A fantastic read. I will definitely be back.

    Reply
  34. sail boat rental
    sail boat rental says:

    Hey there I am so thrilled I found your webpage, I really found you by
    error, while I was searching on Yahoo for something else, Anyways I am here now and would just like to say many
    thanks for a tremendous post and a all round enjoyable blog (I also love the theme/design), I
    don’t have time to look over it all at the moment but I
    have saved it and also added your RSS feeds, so
    when I have time I will be back to read much more, Please do keep up
    the excellent work.

    Look into my blog … sail boat rental

    Reply
  35. slot 88
    slot 88 says:

    I believe that is one of the most vital info for
    me. And i am glad studying your article. However should remark on some common issues, The web site taste is ideal, the articles is in point
    of fact great : D. Excellent task, cheers

    Reply
  36. PV再現
    PV再現 says:

    Great goods from you, man. I’ve understand your
    stuff previous to and you are just too excellent. I actually like what you
    have acquired here, certainly like what you are stating and
    the way in which you say it. You make it enjoyable and you still take care of to keep it wise.
    I can’t wait to read far more from you. This is really a terrific site.

    Reply
  37. Shaunte Muse
    Shaunte Muse says:

    Its like you learn my thoughts! You appear to understand so much about this, like you wrote the book in it or something. I feel that you simply could do with some p.c. to drive the message house a little bit, however instead of that, that is magnificent blog. An excellent read. I will certainly be back.

    my page: https://neuralketo.net

    Reply
  38. zmozeroteriloren
    zmozeroteriloren says:

    Thank you, I’ve just been looking for info approximately this subject for a long time and yours is the greatest I have came upon so far. But, what in regards to the conclusion? Are you positive about the source?

    Reply
  39. Neuronwriter In addition to